Stability and Compatibility
Stability and compatibility testing is to ensure that products maintain their intended physical and chemical quality when stored under various conditions.
Independent analysis gives you confidence in your product
We can tailor our standard test protocols to match particular requirements, or alternatively implement specified protocols, as necessary.
Stability
Assessing the formulation by subjecting a sample to various temperature, humidity and light conditions. The conditions selected should best reflect those that are to be experienced during storage, transport and use.
Compatibility
Conducted in a similar manner to that of a stability test, however, with the focus on the interaction between the primary packaging and formulation as well as its overall functionality.
Temperature Conditions
- -15°C (±5°C)
- Freeze Thaw cycling [-10°C to 40°C over 24 hours] (±2°C)
- 4°C (2 – 8°C)
- 20°C (±1°C)
- 25 (±1°C)
- 30 (±1°C)
- 37 (±1°C)
- 40 (±1°C)
- 45 (±1°C)
- 50 (±1°C)
- 55 (±1°C)
- 60 (±1°C)
Humidity Conditions
- 20°C + (±1°C) / 75%RH (±5%)
- 25°C (±1°C) / 40%RH (±5%)
- 25°C (±1°C) / 60%RH (±5%)
- 30°C (±1°C) / 35%RH (±5%)
- 30°C (±1°C) / 65%RH (±5%)
- 40°C (±1°C) / 75%RH (±5%)
- 40°C + (±1°C) / NMT 25%RH (±5%)
Light Conditions
- North Facing Window
- Instrumental Accelerated Light – SunTest CPS+
Stability Testing Services
Preliminary (Screen) Stability Test
Helps screen formulations during product development.
1 week stress test to determine whether the formulation is robust enough for a full Stability Trial.
Sample Quantity Required: 100ml.
Samples stored in:
- 4°C Control
- Accelerated Condition (Usually 45°C can be adjusted) – Thermal Stability
- Freeze Thaw Cycling (-10°C to 40°C over 24 hours) – Temperature variation
- Intense Instrumental Irradiance Control – Photo Stability
Standard Accelerated Stability / Compatibility Test
A predictive study used to estimate the expiry date
Sample Quantity Required: 500ml / 5 filled packs (minimum)
Samples stored in our standard 5 conditions:
- 4°C, 20°C, 40°C, Window Light & Freeze Thaw Cycling
- 12 week duration with tests conducted at regular intervals
Test services vary upon product type & Client request
Interim updates & images provided throughout the trial, with full report on completion
Real Time Stability / Compatibility Test
As an add-on to the Accelerated Test, additional samples are stored for intended shelf life (up to 30 months for PAO) to determine the actual expiry date
Sample Quantity Required: 200ml / 2 filled packs (minimum)
Samples stored in 2 conditions:
4°C & 20°C
Test duration dependant on the Clients intended shelf life:
6, 12, 24 & 30 months
Bespoke Stability / Compatibility Test
We can tailor a protocol to your requirements, or implement your own protocol based on the relevant tests required to accelerate and predict the effects of normal conditions of storage and use.
Review our storage conditions & testing services to create a protocol that is fitting for your products
We offer a flexible approach that is cost effective, providing a personal and professional service
Compatibility
- Basic Pack Integrity plus Functionality
- pH
- Viscosity (RV-DVE & Small Sample Adaptor)
- Density / SG
- Moisture Analysis
- GC
- Flash Point
Organoleptic Properties
- Colour
- Appearance
- Odour
- Taste